Oke is a former anchor for CNN International's World Weather service at the network's global headquarters in Atlanta, Georgia. She presented weather segments for the programs Your World Today and World News. She also regularly hosted Inside Africa, now fronted by Errol Barnett, a programme that looks into the economic, social and cultural affairs and trends in Africa.
Femi began her career at age 14 working as a junior reporter for the United Kingdom's first talk radio station LBC. During 1993 Femi worked for a cable station called Wire TV, this was pre-Janet Street Porter's L!VE TV. Femi presented several shows for the station, including the popular Soap on the Wire on a Saturday afternoon, with soap opera expert Chris Stacey. In the early 1990s, Femi presented the BBC's flagship educational science programme Science In Action and was also a presenter of Top of the Pops. She has also worked for GMTV, London Weekend Television, Men & Motors and Carlton Television. She joined CNN in 1999, and worked there until 2008. Currently. she hosts The Stream on Al Jazeera English.